NDUFV3 Back

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa

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NCBI Description of NDUFV3
The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NDUFV3 is highly significantly mutated in
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NDUFV3 is significantly mutated in
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NDUFV3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NDUFV3