NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NDUFS3

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.

Community Annotation of NDUFS3 Add / Edit NDUFS3: Annotations

No community annotations yet for NDUFS3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NDUFS3 is highly significantly mutated in
NDUFS3 is significantly mutated in
NDUFS3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NDUFS3