NDUFB6 Back

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa

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NCBI Description of NDUFB6
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified.

Community Annotation of NDUFB6 Add / Edit NDUFB6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NDUFB6 is highly significantly mutated in
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NDUFB6 is significantly mutated in
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NDUFB6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NDUFB6