NDUFB5 Back

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa

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NCBI Description of NDUFB5
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NDUFB5 Add / Edit NDUFB5: Annotations

No community annotations yet for NDUFB5.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NDUFB5 is highly significantly mutated in
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NDUFB5 is significantly mutated in
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NDUFB5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NDUFB5