NDUFAF2 Back

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2

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NCBI Description of NDUFAF2
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NDUFAF2 is highly significantly mutated in
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NDUFAF2 is significantly mutated in
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NDUFAF2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NDUFAF2