NDUFA8 Back

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa

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NCBI Description of NDUFA8
The protein encoded by this gene belongs to the complex I 19 kDA subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NDUFA8 is highly significantly mutated in
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NDUFA8 is significantly mutated in
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NDUFA8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NDUFA8