NDUFA11 Back

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa

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NCBI Description of NDUFA11
This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.

Community Annotation of NDUFA11 Add / Edit NDUFA11: Annotations

No community annotations yet for NDUFA11.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NDUFA11 is highly significantly mutated in
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NDUFA11 is significantly mutated in
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NDUFA11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NDUFA11