NDRG2 Back

NDRG family member 2

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NCBI Description of NDRG2

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Community Annotation of NDRG2 Add / Edit NDRG2: Annotations

No community annotations yet for NDRG2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NDRG2 is highly significantly mutated in
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NDRG2 is significantly mutated in
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NDRG2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NDRG2