NCS1 Back

neuronal calcium sensor 1

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NCBI Description of NCS1
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NCS1 Add / Edit NCS1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NCS1 is highly significantly mutated in
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NCS1 is significantly mutated in
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NCS1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NCS1