NCOA6 Back

nuclear receptor coactivator 6

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NCBI Description of NCOA6
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NCOA6 is highly significantly mutated in
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NCOA6 is significantly mutated in
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NCOA6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NCOA6