NCKAP1L Back

NCK-associated protein 1-like

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NCBI Description of NCKAP1L
This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.

Community Annotation of NCKAP1L Add / Edit NCKAP1L: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NCKAP1L is highly significantly mutated in
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NCKAP1L is significantly mutated in
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NCKAP1L is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NCKAP1L