NCK1 Back

NCK adaptor protein 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NCK1
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.

Community Annotation of NCK1 Add / Edit NCK1: Annotations

No community annotations yet for NCK1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NCK1 is highly significantly mutated in
(none)
NCK1 is significantly mutated in
(none)
NCK1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NCK1