NCF1 Back

neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NCF1

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Community Annotation of NCF1 Add / Edit NCF1: Annotations

No community annotations yet for NCF1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NCF1 is highly significantly mutated in
NCF1 is significantly mutated in
NCF1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NCF1