NCAM1 Back

neural cell adhesion molecule 1

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NCBI Description of NCAM1

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants.

Community Annotation of NCAM1 Add / Edit NCAM1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NCAM1 is highly significantly mutated in
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NCAM1 is significantly mutated in
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NCAM1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NCAM1