NAT8 Back

N-acetyltransferase 8

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NCBI Description of NAT8
This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene.

Community Annotation of NAT8 Add / Edit NAT8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NAT8 is highly significantly mutated in
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NAT8 is significantly mutated in
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NAT8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NAT8