NCBI Description of NAT2
|This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2).|
Community Annotation of NAT2 Add / Edit NAT2: Annotations
No community annotations yet for NAT2.
Click on a tumor type to see its full list of significant genes.