NAT1 Back

N-acetyltransferase 1 (arylamine N-acetyltransferase)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NAT1
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NAT1 Add / Edit NAT1: Annotations

No community annotations yet for NAT1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NAT1 is highly significantly mutated in
(none)
NAT1 is significantly mutated in
(none)
NAT1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NAT1