NALCN Back

sodium leak channel, non-selective

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NCBI Description of NALCN
NALCN forms a voltage-independent, nonselective, noninactivating cation channel permeable to Na+, K+, and Ca(2+). It is responsible for the neuronal background sodium leak conductance (Lu et al., 2007 [PubMed 17448995]).[supplied by OMIM, Mar 2008].

Community Annotation of NALCN Add / Edit NALCN: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NALCN is highly significantly mutated in
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NALCN is significantly mutated in
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NALCN is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NALCN