NADSYN1 Back

NAD synthetase 1

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NCBI Description of NADSYN1

Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).[supplied by OMIM, Apr 2004].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NADSYN1 is highly significantly mutated in
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NADSYN1 is significantly mutated in
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NADSYN1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NADSYN1