NAA10 Back

N(alpha)-acetyltransferase 10, NatA catalytic subunit

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NCBI Description of NAA10
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants.

Community Annotation of NAA10 Add / Edit NAA10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NAA10 is highly significantly mutated in
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NAA10 is significantly mutated in
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NAA10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NAA10