N6AMT1 Back

N-6 adenine-specific DNA methyltransferase 1 (putative)

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NCBI Description of N6AMT1

This gene encodes protein methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 11.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

N6AMT1 is highly significantly mutated in
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N6AMT1 is significantly mutated in
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N6AMT1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for N6AMT1