MYOD1 Back

myogenic differentiation 1

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NCBI Description of MYOD1

This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

Community Annotation of MYOD1 Add / Edit MYOD1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYOD1 is highly significantly mutated in
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MYOD1 is significantly mutated in
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MYOD1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MYOD1