MYO1C Back

myosin IC

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MYO1C
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.

Community Annotation of MYO1C Add / Edit MYO1C: Annotations

No community annotations yet for MYO1C.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYO1C is highly significantly mutated in
(none)
MYO1C is significantly mutated in
(none)
MYO1C is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MYO1C