MYLK3 Back

myosin light chain kinase 3

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NCBI Description of MYLK3
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYLK3 is highly significantly mutated in
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MYLK3 is significantly mutated in
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MYLK3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MYLK3