MYL3 Back

myosin, light chain 3, alkali; ventricular, skeletal, slow

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NCBI Description of MYL3

MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MYL3 is highly significantly mutated in
MYL3 is significantly mutated in
MYL3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MYL3