MYL2 Back

myosin, light chain 2, regulatory, cardiac, slow

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NCBI Description of MYL2
Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYL2 is highly significantly mutated in
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MYL2 is significantly mutated in
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MYL2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MYL2