MYH14 Back

myosin, heavy chain 14

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NCBI Description of MYH14
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MYH14 Add / Edit MYH14: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYH14 is highly significantly mutated in
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MYH14 is significantly mutated in
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MYH14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MYH14