MYH10 Back

myosin, heavy chain 10, non-muscle

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NCBI Description of MYH10
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MYH10 Add / Edit MYH10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYH10 is highly significantly mutated in
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MYH10 is significantly mutated in
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MYH10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MYH10