MYH1 Back

myosin, heavy chain 1, skeletal muscle, adult

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NCBI Description of MYH1

Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development.

Community Annotation of MYH1 Add / Edit MYH1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYH1 is highly significantly mutated in
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MYH1 is significantly mutated in
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MYH1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MYH1