MVD Back

mevalonate (diphospho) decarboxylase

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NCBI Description of MVD
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.

Community Annotation of MVD Add / Edit MVD: Annotations

No community annotations yet for MVD.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MVD is highly significantly mutated in
(none)
MVD is significantly mutated in
(none)
MVD is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MVD