MUC6 Back

mucin 6, oligomeric mucus/gel-forming

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NCBI Description of MUC6

The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993 [PubMed 7680650]).[supplied by OMIM, Dec 2010]. Sequence Note: The RefSeq transcript was derived from genomic sequence based on transcript alignments and the published description of the gene structure (PubMed ID 15081123).

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MUC6 is highly significantly mutated in
MUC6 is significantly mutated in
MUC6 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MUC6