MTX2 Back

metaxin 2

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NCBI Description of MTX2
The protein encoded by this gene is highly similar to the metaxin 2 protein from mouse, which has been shown to interact with the mitochondrial membrane protein metaxin 1. Because of this similarity, it is thought that the encoded protein is peripherally associated with the cytosolic face of the outer mitochondrial membrane, and that it is involved in the import of proteins into the mitochondrion. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7.

Community Annotation of MTX2 Add / Edit MTX2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MTX2 is highly significantly mutated in
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MTX2 is significantly mutated in
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MTX2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MTX2