MTTP Back

microsomal triglyceride transfer protein

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NCBI Description of MTTP
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Community Annotation of MTTP Add / Edit MTTP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MTTP is highly significantly mutated in
(none)
MTTP is significantly mutated in
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MTTP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MTTP