MTPAP Back

mitochondrial poly(A) polymerase

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NCBI Description of MTPAP
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.

Community Annotation of MTPAP Add / Edit MTPAP: Annotations

No community annotations yet for MTPAP.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MTPAP is highly significantly mutated in
(none)
MTPAP is significantly mutated in
(none)
MTPAP is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MTPAP