MTO1 Back

mitochondrial translation optimization 1 homolog (S. cerevisiae)

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NCBI Description of MTO1
This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MTO1 Add / Edit MTO1: Annotations

No community annotations yet for MTO1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MTO1 is highly significantly mutated in
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MTO1 is significantly mutated in
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MTO1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MTO1