MTNR1B Back

melatonin receptor 1B

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MTNR1B
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.

Community Annotation of MTNR1B Add / Edit MTNR1B: Annotations

No community annotations yet for MTNR1B.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MTNR1B is highly significantly mutated in
(none)
MTNR1B is significantly mutated in
(none)
MTNR1B is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MTNR1B