MTMR7 Back

myotubularin related protein 7

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MTMR7
This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5.

Community Annotation of MTMR7 Add / Edit MTMR7: Annotations

No community annotations yet for MTMR7.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MTMR7 is highly significantly mutated in
(none)
MTMR7 is significantly mutated in
(none)
MTMR7 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MTMR7