MSRB3 Back

methionine sulfoxide reductase B3

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NCBI Description of MSRB3
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MSRB3 is highly significantly mutated in
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MSRB3 is significantly mutated in
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MSRB3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MSRB3