MSRA Back

methionine sulfoxide reductase A

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NCBI Description of MSRA
This protein is ubiquitous and highly conserved. It carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. Its proposed function is the repair of oxidative damage to proteins to restore biological activity. Three transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MSRA is highly significantly mutated in
(none)
MSRA is significantly mutated in
(none)
MSRA is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MSRA