MS4A5 Back

membrane-spanning 4-domains, subfamily A, member 5

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NCBI Description of MS4A5

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Though this member is not expressed in hematopoietic cells specifically, it may be involved in signal transduction like many of its related family members. The gene encoding this protein is localized to 11q12, among a cluster of family members.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MS4A5 is highly significantly mutated in
MS4A5 is significantly mutated in
MS4A5 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MS4A5