MS4A3 Back

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)

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NCBI Description of MS4A3

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MS4A3 is highly significantly mutated in
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MS4A3 is significantly mutated in
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MS4A3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MS4A3