MRPS28 Back

mitochondrial ribosomal protein S28

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MRPS28
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature.

Community Annotation of MRPS28 Add / Edit MRPS28: Annotations

No community annotations yet for MRPS28.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MRPS28 is highly significantly mutated in
(none)
MRPS28 is significantly mutated in
(none)
MRPS28 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MRPS28