MRFAP1 Back

Mof4 family associated protein 1

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NCBI Description of MRFAP1
This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants.

Community Annotation of MRFAP1 Add / Edit MRFAP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MRFAP1 is highly significantly mutated in
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MRFAP1 is significantly mutated in
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MRFAP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MRFAP1