MRAS Back

muscle RAS oncogene homolog

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NCBI Description of MRAS
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of MRAS Add / Edit MRAS: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MRAS is highly significantly mutated in
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MRAS is significantly mutated in
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MRAS is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MRAS