MPDU1 Back

mannose-P-dolichol utilization defect 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MPDU1
This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants.

Community Annotation of MPDU1 Add / Edit MPDU1: Annotations

No community annotations yet for MPDU1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MPDU1 is highly significantly mutated in
(none)
MPDU1 is significantly mutated in
(none)
MPDU1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MPDU1