MOS Back

v-mos Moloney murine sarcoma viral oncogene homolog

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NCBI Description of MOS

MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009].

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MOS is highly significantly mutated in
MOS is significantly mutated in
MOS is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MOS