MOG Back

myelin oligodendrocyte glycoprotein

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NCBI Description of MOG
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of MOG Add / Edit MOG: Annotations

No community annotations yet for MOG.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MOG is highly significantly mutated in
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MOG is significantly mutated in
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MOG is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MOG