MOAP1 Back

modulator of apoptosis 1

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NCBI Description of MOAP1
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.

Community Annotation of MOAP1 Add / Edit MOAP1: Annotations

No community annotations yet for MOAP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MOAP1 is highly significantly mutated in
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MOAP1 is significantly mutated in
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MOAP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MOAP1