MNX1 Back

motor neuron and pancreas homeobox 1

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NCBI Description of MNX1
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MNX1 Add / Edit MNX1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MNX1 is highly significantly mutated in
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MNX1 is significantly mutated in
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MNX1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MNX1