MND1 Back

meiotic nuclear divisions 1 homolog (S. cerevisiae)

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NCBI Description of MND1
The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MND1 is highly significantly mutated in
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MND1 is significantly mutated in
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MND1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MND1